US Highways Route - US 20 [I]
| Route | From | To | Miles | States passed through | Replaced by | Notes |
| US 20 [I] | Boston, MA | Yellowstone NP, WY | 2376 (2542) | MA NY PA OH IN IL IA NE WY | NY-39 US 20S Alt US 20 OH-511 IA-939 | Since 1926; /N//S/ E Leg |
| US 20 [II] | Yellowstone NP, MT | Newport, OR | 861 | MT ID OR | Alt US 93 US 93 US 30 | Since 1940; W Leg |
| (US 120) | (Philadelphia, PA) | (Erie, PA) | (447) | (PA) | US 13 US 422 [I] US 122 [II] PA-61 PA-14 PA-147 PA-405 I-180 US 220 PA-120 US 219 US 6 US 6 US 6N [II] PA-97 | Exist 1926-1967; E trunc Reading, PA 1927; Lock Haven, PA 1934; W exten Erie, PA 1927; W trunc Ridgeway, PA 1927 |
| US 220 | Waverly, NY | Rockingham, NC | 678 | NY PA MD WV VA NC | US 15 US 6 PA-405 PA-150 PA-550 PA-36 MD-807 WV-972 US 50 Alt US 220 | Since 1926; S exten New Creek, WV 1930; Curr 1934 |
| (US 320) | (Shoshoni, WY) | (Riverton, WY) | (26) | (WY) | WY-320 US 26 WY-789 | Exist 1926-1938 |
| (US 420) | (Deaver, WY) | (Cody, WY) | (41) | (WY) | US 116 US 14 WY-114 WY-14 Alt US 14 | Exist 1926-1933 |
| US 22 | Newark, NJ | Cincinnati, OH | 651 (663) | NJ PA WV OH | NJ-28 NJ-173 US 222 US 422 US 322 PA-147 PA-34 | Since 1926; E trunc Somerville, NJ 1936; E exten 1936; W extnd 1932 |
| (US 122) [I] | (Haverstraw, NY) | (Wilmington, DE) | (165) | (NY) (NJ) (PA) (DE) | US 202 NJ-523 US 202 NJ-179 US 202 | Exist 1926-1934; N exten 1934 |
| (US 122) [II] | (Oxford, PA) | (Northumberland, PA) | (128) | (PA) | PA-10 PA-61 PA-147 | Exist 1935-1963; S trunc Morgantown, PA 1956 |
| US 222 | (Allentown, PA) Dorneyville, PA | Conowingo, MD (Perryville, MD) | 100 (116) | PA MD | PA-222 PA-12 PA-272 MD-222 | Since 1926; S trunc 1995 |
| US 322 | Atlantic City, NJ | Cleveland, OH | 494 | NJ PA OH | NJ-324 PA-581 PA-230 US 22 PA-453 US 220 PA-350 PA-46 PA-970 PA-53 PA-879 US 219 | Since 1926; E exten 1936; Was ferry |
| US 422 [I] | (Tacony, PA) King of Prussia, PA | Hummelstown, PA (Harrisburg, PA) | 88 (117) | PA | PA-562 US 322 | Since 1927; E Leg; Orig W end Reading, PA; W exten 1932; E trunc Lafayette Hill, PA 1938; E exten Tacony, PA 1938; E trunc Norristown, PA 1951; E exten Philadelphia, PA 1951; Curr E trunc 1985 |
| US 422 [II] | (Ebensburg, PA +) Revloc, PA | Cleveland, OH | 184 (186) | PA OH | PA-45 US 22 PA-271 PA-488 US 19 OH-87 | Since 1926; W Leg; E trunc 1991 |
| US 522 | Selinsgrove, PA | Powhatan, VA + | 308 (317) | PA MD WV VA | US 622 | Since 1926; S trunc Lewiston, PA 1927; S exten Hancock, MD 1927; Curr S 1944 |
| (US 622) | (Mount Union, PA) | (Hancock, MD) | (66) | (PA) (MD) | US 522 | Exist 1926-1927 |
| US 24 | Clarkston, MI | Dowd, CO (Grand Junction, CO) | 1540 (1709) | MI OH IN IL MO KS CO | OH-65 OH-110 IN-930 IL-9 IL-78 MO-224 US 6 I-70 CO-24 | Since 1926; W exten 1936; W trunc 1975; E exten 1987 |
| (US 124) | (Peoria, IL) | (Biggsville, IL +) | (80) | (IL) | IL-116 IL-78 IL-8 IL-97 US 150 | Exist 1926-1939; W trunc Farmington, IL 1934; W exten 1934 |
| US 224 | New Castle, PA | Huntington, IN | 287 | PA OH IN | Bus US 422 OH-421 OH-100 OH-18 | Since 1934; E trunc 1977 |
| US 26 | Ogallala, NE | Cannon Beach Jct., OR (Astoria, OR) | 1526 (1557) | NE WY ID OR | NE-92 US 26N | Since 1926; /N/ W Exten Alpine, WY 1949; Idaho Falls, ID 1951; Curr 1952; W trunc 2005 |
| (US 126) | (Prineville, OR) | (Florence, OR) | (131) | (OR) | OR-126 | Exist 1952-1972 |
| (US 28) | (Ontario, OR) | (Florence, OR) | (462) | (OR) | US 26 US 126 OR-126 OR-242 US 126 OR-126 US 99 OR-99 OR-36 OR-126 | Exist 1926-1952; W Trunc Eugene, OR 1937 |
U.S. Highways
| US 1 | US 11 | US 21 | US 31 | US 41 |
| US 51 | US 61 | US 71 | US 81 | US 91 |
| US 2[I] | US 10 [I] | US 20 [I] | US 30 | US 40 |
| US 50 | US 60 | US 70 | US 80 | US 90 |